Cyclic neutropenia in grey collie dogs.

By JOHN E. LUND, GEoRGE A. PADCEYF AND RIChARD L. Orr C YCLIC NEUTROPENIA is a rare hematologic disorder characterized by the chronic, cyclical recurrence of severe neutropenia which has previously 1)een described only in humans. The neutropenia recurs approximately every 21 days and lasts from 3 to 10 days. The clinical manifestations of the disease are observed during the neutropenic phase of the cycle and include fever, malaise, oral ulcers, furunculosis and lymphadenitis. Page and Good’ reviewed the literature prior to 1957. Reimann2 recently reviewed 42 cases of the disease which he termed periodic myelodysplasia. The purpose of this paper is to report the finding of a similar syndrome in grey (silver) collies.